SRCosmos:

Order of appearence	Full citation	SRCosmos Link
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2	Michaelidou S, presentation at Arhena Conference 8/5/04, available web:www.arehna.di.uoa.gr
3	IFCS/FORUM 2003, Bangkok- Document IV/14w
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8	Howard C, presentation at Arhena Conference 8/5/04, available web:www.arehna.di.uoa.gr
9	European Commission (2004). Communication from the Commission to the Council, the European Parliament, the European Economic and Social Committee on the European & Health Action Plan 2004-2010. Brussels, European Commission (COM(2004) 416 final).
10	Gee D, et al. (2002). Late lessons from early warnings: the precautionary principle 1896–2000. Copenhagen, European Environment Agency, Introduction, p. 13
11	WHO: Dealing with the uncertainty, EUR/04/5046267/11
12	Gee D, presentation at Arhena Conference 8/5/04, available web:www.arehna.di.uoa.gr

Keywords
Abstract	The children, from the prenatal period through adolescence often react differently to chemicals than do their adult counterparts because, they have different exposures and behavior patterns, metabolism, and special vulnerabilities determined also by critical time windows of development. Their systems are still developing, often making them less able than adults to metabolize, detoxify, and excrete toxins. The enhanced rate of cell division and the longer life span during which cancers initiated in childhood can develop, can significantly affect cancer development. Of particular concern are the potential effects of Endocrine and Cell Signaling disrupters especially when exposure occurs during “critical windows of development”. Does present Risk Assessment consider children’s special sensitivity, enhanced exposures and windows of vulnerability adequately? What about combined effects of different chemicals, or effects on endocrine and cell signalling systems occurring at extreme low levels (ppt or ppq)? In view of the unavoidable uncertainties and the vast knowledge and evidence of potential severe hazards to children, the rational application of the Precautionary Principle remains an indispensable component of the risk management [1-2].
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Name	Affiliation	Home page	e-mail	Total pubs
Canna-Michaelidou S	Labs Environmental Chemistry I & Ecotoxicology, State General Laboratory Kimonos 44, 1451 Nicosia, Cyprus		mchristodoulidou@sgl.moh.gov.cy	3